Why titration exists
GLP-1 medications are commonly increased gradually to improve tolerability. The right schedule depends on the specific medication, formulation, response, and side effects.
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Clinician discussion guide
GLP-1 Dosage and Titration Guide
Compare common semaglutide and tirzepatide titration patterns and questions to discuss with a licensed clinician.
Enter your detailsGLP-1 Dosage and Titration Guide
Weeks 1-40.25 mg weeklyStarter phase
Weeks 5-80.5 mg weeklyCommon first increase
Weeks 9-121 mg weeklyIf tolerated and clinically appropriate
Later1.7-2.4 mg weeklyDepends on product and care plan
This is educational only. Your prescribed dose, concentration, and instructions may differ.
This is not a prescription
Dose changes should be made only with a licensed clinician. Compounded and branded medications can have different concentrations, pens, instructions, and safety considerations.
What to do with the result
Save the number, compare it with your goals, and bring it into the Caliber intake. A clinician-reviewed plan can account for medical history, medications, tolerability, and whether GLP-1 therapy is appropriate.
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