Is this the same as Ozempic?
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Same active molecule, compounded by a 503B pharmacy under federal
exemption while branded supply remains in shortage.
Compounded medications are not FDA-approved,
though semaglutide as a molecule is.
Will I lose muscle?
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Some lean mass loss is normal in any caloric deficit. The protocol
includes resistance-training guidance, protein targets, and
quarterly body-composition tracking.
Side effects?
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Nausea, constipation, fatigue during dose escalations — most resolve
within a week. The Companion Kit ships with month one.
Can I cancel?
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Yes. Cancel future renewals from the member portal without a
retention call or 30-day notice. The 365-day Weight Loss Warranty is
separate and applies only to eligible members who complete the
required program terms.
What does pricing include?
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Pricing includes physician review, medication when prescribed,
titration, the companion kit, shipping, support, and quarterly
bloodwork. HSA and FSA cards are accepted, and you can cancel after
any month without a retention call.
What states?
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Florida, Texas, and Georgia today. We check eligibility against
your state at the start of the assessment — if we're not live where
you are yet, you can join the waitlist for your state.
How quickly will I see results?
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Appetite signaling typically calibrates in the first 4–6 weeks.
Bloodwork (HbA1c, fasting insulin, lipids) usually shifts by month
three. Body-composition changes follow the metabolic shift, not
the other way around. The protocol is built for 12–24 months of
stable use.
Do you accept insurance?
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No. Caliber is direct-pay — one of the reasons pricing stays
transparent and consistent. HSA and FSA cards
are accepted. Most members find Caliber significantly
cheaper than branded GLP-1s through insurance once deductibles
and prior-auth friction are factored in.
What if I'm already on a GLP-1 from another provider?
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Tell us in the assessment. Your reviewing physician will pick up
where your previous protocol left off — same dose, similar
titration cadence — without restarting you at the bottom. Bring
your most recent prescription label if you have it.
Do I have to inject myself?
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Yes. Semaglutide is a subcutaneous injection — once weekly, into
the abdomen or thigh, with a 27-gauge insulin needle. Most
members describe it as roughly the discomfort of a thumbnail
press. The Companion Kit and your physician walk you through it.
What if I have a question between physician check-ins?
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Direct-message your physician from the member portal. Same-day
response on weekdays, next business day on weekends. Not a
chatbot — the same person who designed your protocol.
Can I pause my protocol?
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Yes — pause for travel, surgery, or just a break, in one tap from
the portal. Paused months aren't charged. Resume when you're
ready; your physician adjusts your re-entry dose if you've been
off the protocol for more than four weeks.
Is Caliber appropriate for me?
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A US-licensed physician makes that call after your assessment.
Caliber is typically prescribed for adults with a BMI of 27+
(with at least one related condition) or 30+ on its own.
Compounded semaglutide isn't appropriate during pregnancy or
breastfeeding, with a personal/family history of medullary
thyroid cancer or MEN 2, or with a few other specific conditions
your clinician will screen for.
Is this safe?
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Semaglutide has been studied in trials totaling tens of thousands
of patients, with cardiovascular outcomes (SELECT, 2023) showing
a 20% reduction in major adverse events. Compounded
versions are not FDA-approved — our 503B partner
(Empower Pharmacy) compounds under cGMP standards with per-batch
potency, sterility, pH, and endotoxicity testing.
What if it doesn't work for me?
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If you complete 12 consecutive months of eligible Caliber care,
follow the prescribed protocol, and do not see clinically
meaningful weight loss, you may qualify for the Caliber Weight
Loss Warranty.
Terms apply.
You can still cancel any time.